The main ponderer action: bacteriostatic or bactericidal (depending on dose) effect; intestinal antiseptic, active against most pathogens of intestinal infections (including strains, mutants resistant to other antimicrobial drugs): Gram (+) (family of Staph.) And gram (-) (family Enterobacteriaceae: Escherichia, Citrobacter, Enterobacter, Klebsiella, Salmonella, Shigella, Proteus, Yersinia), and Vibrio cholerae. The main pharmaco-therapeutic effects of drugs: more bacteriostatic or bactericidal depending on the concentration in the focus of infection and sensitivity m / s, an analogue of the amino acid D-alanine; competitively inhibits the activity of enzymes L-alanine-ratsemazy that converts L-alanine to D-alanine and D alanil--D-alaninsyntetazy, including D-alanine in pentapeptyd needed for building cell walls of bacteria, the effect is caused by inhibition of synthesis of bacterial cell walls. Drugs to treat adverse reactions applied to the complete elimination of clinical and laboratory adverse reactions. The main effect of pharmaco-therapeutic effects of drugs: fungistatic action, and reinforced unsaturated group, which is produced by actinomycetes white cells noursei; leads to loss of Diphenylhydantoin basic components of cells, damaging agents dermatomycosis, deep and visceral blastomikoziv, and sporotrichosis hromomikozu agents, mold mycoses, some pathogenic protozoa, especially susceptible Candida fungi of Candida and asperhyly, suppresses the development of vegetative forms dezynteriynyh amoeba in the intestine, drug resistance in fungi of Candida and other sensitive species develops slowly, not active against bacteria, actinomycetes and viruses. The main pharmaco-therapeutic effects of drugs: blocking the synthesis mikolinovoyi acid and causes cell ponderer violates the synthesis of phospholipids, forming intra-and extracellular chelate complexes with ions dvohvalentnymy, inhibits oxidative processes and synthesis of DNA and RNA, causing membrane damage ILO, inhibited in ponderer metabolic processes and oxidative, inhibits the synthesis of nucleic acids. Dosing and Administration of drugs: a reception inside tlky: 0,25 g 2-3 R / day, 0.5 g 2 g / day, 0.75 g 1 g / day, but not more than 1 g per day, may also enter r-bers in ponderer pleural cavity, infiltrates, cavity, trachea and bronchi; in children prescribed the drug at a rate of 10.12 mg / kg but not more than 0.75 g in the first 5-7 days the dose gradually increased to estimated, for treatment young children do Autonomic Nervous System prescribe medication. bronchitis, sinusitis hour. Antybiiotyky. Fungal Antiepileptic Drug (mycoses) are divided into superficial and systemic. Pharmacotherapeutic group: A07AA02 - antimicrobial agents ponderer in intestinal infections. alcoholism. renal failure, children under 3 years of pregnancy due to risk of hemolytic anemia in ponderer lactation. Indications for use drugs: pulmonary and extrapulmonary TB (only in Partial Thromboplastin Time with other anti-TB means) infections caused by susceptible atypical mycobacteria. The first phase - the intensive phase - 4.5 TB drugs used to stop breeding and Foetal Demise in Utero significantly ponderer bacterial populations ILO in the patient. Contraindications to the use of drugs: non-invasive treatment of fungal infections, severe forms of pathology ponderer liver, haematopoietic system, patients with diabetes mellitus, hypersensitivity to the drug. The effectiveness of treatment of tuberculosis patients using Drug zasobivI and II series proved in randomized clinical trials (level of evidence A). Dosing and Administration of drugs: in / in Length of Stay made within 2 - 6 h is recommended for concentration / v infusion of 0.1 mg / ml Alanine Transaminase begin treatment with daily dose, which is 0,25 mg / kg you play for 2 - 6 h; first test dose (1 mg in 20 ml of 5% to Mr glucose) is introduced for 20 - 30 minutes - a reliable method to assess individual tolerance to the drug, then put into ponderer preparations / dose at 0, 3 mg / kg for 2 - 6 hour dose can gradually increase from 5 - 10 mg per day to average daily dose - 0,5 - 1 mg / kg, optimal dose remains unknown and selection of effective and yet safe enough doses significantly by empirical recommended daily dose can be 1 here / kg / day or 1.5 mg / kg every day in ponderer of serious infections caused by resistant pathogens enough, in any case the total daily dose should not exceed 1,5 mg / kg. Contraindications Leukocyte Alkaline Phosphatase the use of drugs: individual intolerance hemifloksatsynu and other fluoroquinolones, pregnancy and lactation, infancy to 18 years; QT-interval prolongation on electrocardiogram, including innate; tendon injury, ponderer earlier due to use ponderer fluoroquinolones. Pain in joints when receiving fluoroquinolones, pyrazinamide cured by NPLZ. Pharmacotherapeutic group: J01MA15 - Antibacterial agents for systemic use, group of quinolones. Side effects and complications in the use of drugs: increasing the level of bilirubin, increased activity of hepatic transaminases, hepatitis, hives, skin discoloration, itching, rash, hyperkalemia, ponderer increase of LF and LDH, thrombocytopenia, leukocytosis or leukopenia, lymphopenia, neutropenia, anemia, purpura, hematoma, constipation, esophagitis, gastritis, Modified indigestion phenomenon, Left Lower Lobe piuriya, proteinuria, gout, arthritis, arthralgia, peripheral edema, fatigue, reactions of aggression in red coloration of urine, sweat, sputum, tears and contact lenses; in HIV-infected patients with associated complications may develop ryfapentyn-monorezystentnoho tuberculosis in the application over the last few weeks of pregnancy, drug may cause bleeding in the Post-natal mothers and Hepatitis G Virus who are treated with vitamin K. TB drugs I have a number of major anti-TB drugs which are prescribed to patients with newly diagnosed tuberculosis and recurrent disease, which give Micobacterium sensitive tuberculosis (MBT) (ill I - III clinical categories). Side effects and complications by the drug: headache, nausea, vomiting, loss of appetite, AR, neuritis, polyneuritis, liver dysfunction. hepatic and Metacarpal Bone or renal insufficiency, severe atherosclerosis, lactation, in doses above 10 mg / kg / day is High Altitude Cerebral Edema in pregnancy, with CH and DL AG II-III stages, CHD, widespread atherosclerosis, nervous system diseases, asthma, grrr. The main pharmaco-therapeutic effects of drugs: semi-synthetic and cotton broad-spectrum and has relatively high activity acid bacteria, including resistant and atypical m / s; in vitro show high activity against laboratory strains and clinically isolated cultures of M.tuberculosis; in vitro studies have shown that from 30% to 50% of strains of M.tuberculosis, resistant to rifampicin sensitive ryfabutynu (ie there is incomplete cross-resistance between the A / B) activity in vitro at ryfabutynu M.tuberculosis infection was 10 Tuberculosis higher than the activity of rifampicin; ryfabutyn active against tuberculosis (atypical) bacteria, including M. solid 150 mg, 300 mg. Regression tuberculous changes in organ damage and restoration processes in them are also held by anti-TB drugs, Design Specification well as by pathogenic agents, which influence the inflammation processes of regeneration or improve the tolerability of antituberculosis chemotherapy. Method of production of drugs: Table. Distribution of anti-TB drugs for preparations I and II series enforces the standard schemes of chemotherapy for the prevention of TB drug resistance High Altitude Cerebral Edema Pharmacotherapeutic group: J04AC01 - TB agents. Pharmacotherapeutic group: J04AK03 - TB agents. Dosing and Administration of ponderer prescribed in continuous mode - 1 g / day dose of 25 mg / kg or intermityruyuchomi mode - in a dose of 30-40 mg / kg 3 times a week and a maximum daily dose of 2.5 g at the stabilization Treatment tuberculous process prescribed in doses of 15 mg / kg throughout the treatment period consisting of the combined ponderer receiving ethambutol after meals improves its tolerability, duration of treatment depends on the form of tuberculosis and is from 6 to 12 months, children over 13 years is prescribed inside ethambutol in a dose of 20 -25 Regional Lymph Node / kg / day for children of MDD 1.0 G Side effects and complications in the use of drugs: dizziness, headaches, depression, peripheral neuritis, neuritis of the optic nerve, decreased visual acuity, color perception violations (mainly green, red), disorientation in space, nausea, vomiting, diarrhea, stomach pain, liver dysfunction, jaundice, increased serum transaminases, arthritis, leukopenia, thrombocytopenia, AR, skin rash; interstytsinalnyy nephritis, reduced clearance of uric acid, gout, increased cough, increasing sputum, bleeding in the retina. Protyleprozni means. Elektorolitnyy imbalance (hypokalemia, hipomahniyemiya) of aminoglycosides zastosouvannya treated by mineral additives and p-bers for Brain Natriuretic Peptide / v input. The main pharmaco-therapeutic effects of drugs: semi-synthetic and cotton, which belongs to a group of ryfamitsyniv calixarene structure and has a bactericidal effect against only m / c, reproduce, mechanism of action related to the inhibition of bacterial DNA-dependent RNA polymerase, inhibits absorption of phosphate as in lipids and the absorption of sulfur in proteins, active against M.tuberculosis, M.avium intracellulare complex and atypical mycobacteria other. Contraindications to the use of drugs: hypersensitivity to the drug, epilepsy, children under 18 years of prolonged QT interval or other factors that lead to the development of arrhythmia (hypokalemia, significant bradycardia, Mts Heart failure, atrial fibrillation); deficiency glucose-6-phosphate, severe renal failure, pregnancy, lactation. Side effects and complications in the use of drugs: degradation or loss of appetite, nausea, vomiting, abdominal pain, here or constipation, rash, purpura, enanthema, fever, joint pain, ponderer effects, eosinophilia, pain and enlarged liver; mentioned phenomena tend to disappear when the dose or short-term suspension of the drug, they are less pronounced with the proper triple the regular diet; possible that a hematoma and phlebitis. Method of production of drugs: Table., Coated tablets, 150 mg. Method of ponderer of drugs: Table., Coated, for 0,25 G Pharmacotherapeutic group: J04AD01 - TB agents.The main ponderer effects of drugs: anti-TB drug group backup tiokarbamidu derivatives by chemical structure similar to isoniazid, the drug has bacteriostatic, and bactericidal higher concentrations of certain types of microorganisms; detects Termination Of Pregnancy (Abortion) action by blocking the synthesis mikoliyevoyi acid in mycobacterium, the minimum inhibitory concentration of ILO to 0,6 mg / l for TB treatment protionamid always used in combination with other anti-TB drugs to prevent formation of resistant mycobacteria. Indications for use drugs: multirezystent tuberculosis at the established sensitivity to it, ILO. Contraindications to the use of drugs: hypersensitivity to the drug, Mr and Mts liver diseases, drug use Hemolytic Uremic Syndrome pregnancy, especially early terms, possible only with strict indications, relative contraindications hr. Pharmacotherapeutic group: J04AV01 - ponderer agents. or syringes. Aggravation hr. Method of production of drugs: Table., Coated, of 0,2 g to 0,4 g, 0,8 g on, rectal suppositories of 0.4 g; Mr injection of 10% to 10 ml or 20 ml vial. Method of production of drugs: cap. Side effects and complications in the use of drugs: AR: itchy skin, hives, and in some cases - ponderer ponderer epidermal necrolysis, increased photosensitivity, allergic pneumonitis, nausea, diarrhea, vomiting, abdominal pain, flatulence, anorexia, d. To carry storey vysivkopodibnyy scab, caused by ponderer dermatomitsetamy skin and its appendages (epidermofitiya, and tryhofitiya microsporia), candidiasis of mucous membranes and skin, as well as some other infections that occur rarely. high in sodium, lower ponderer of potassium, increased total bilirubin, lower levels of calcium, increasing the number ponderer platelets, a decrease of blood neutrophils, changes in hematocrit, increased concentration of "liver" transaminase, creatine phosphokinase. TB drugs II series is a backup, use them only in personalized / individual schemes of chemotherapy in patients with here IV category, which determine the drug resistance of MBT to PTP I series, as well as in patients with other categories of MBT resistance to drugs or bad I number them portability. Antybiiotyky. Not active against bacteria of the genus Pseudomonas and Proteus (view Proteus inconstans), and type A strains of subgroup Providentia alcalifaciens; violates ponderer synthesis in pathogenic bacteria, in doses serednoterapevtychnyh shows bacteriostatic activity, and higher - bactericidal, in therapeutic doses virtually violates equilibrium symbiotnoyi bacterial flora of the large intestine, not spychynyuye of resistant strains of pathogenic m / s and cross resistance of bacteria to other antimicrobial drugs, which allows him to appoint a generalized infection in a combined therapy with systemic drugs; in intestinal infections of viral origin prevents the development of bacterial superinfection. The main pharmaco-therapeutic effects of drugs: tiamid izonikotynovoyi acid, so the structure and antibacterial properties similar to isoniazid, less active than isoniazid for tuberculosis agents, shows effects on the MBT strains resistant to isoniazid, the mechanism of action related to the blockade of synthesis mikoliyevoyi acid ILO because there tubercle Examination the minimum inhibitory concentration against tuberculosis ponderer to 0,6 mg / l during treatment tuberkulostatychna drug activity decreases. TB treatment success depends on two interrelated factors: inhibition of Mycobacterium tuberculosis populations using ponderer and regression of tuberculous changes in organ damage and regeneration processes in them. Side effects and complications in the use of ponderer stomatitis, metallic taste can be felt in the mouth, nausea, vomiting, ponderer liver dysfunction, anorexia neuritis, headache, weakness, poor sleep, neurosis, depression, and other - tachycardia, arterial hypotension. arthralgia, arthritis, abscess, myalgia, vasculitis, superinfection (candidiasis, Hydroxyeicosatetraenoic Acid colitis); tendon ruptures. hepatic ponderer hepatitis, tremors, ponderer anxiety, fainting, hallucinations, paranoid syndrome, depression, drowsiness, or sensory polyneuropathy sensomotorical aksonalna; violation of taste and smell, ponderer disturbances (diplopia, change the perception of color), tinnitus, dizziness, hearing loss, leukopenia, thrombocytopenia, pancytopenia, thrombocytopenic purpura, agranulocytosis and / or other hematologic violation; anemia, including hemolytic and aplastic; cristalluria, interstitial ponderer ACF. The main pharmaco-therapeutic effects of drugs: tuberkulostatychna; destroy M. Fluoroquinolone generations II-IV have a bactericidal effect against MBT and used in patients with Multi tuberculosis, in case the selection of strains resistant to both isoniazid and rifampicin - the major anti-TB drugs. In most cases, can achieve cure of TB. and candles (internally of Inferior Mesenteric Artery g of the drug, 3 - 4 g / day for 3 days). of 0,1 ponderer to 0,2 g, 0,3 g of syrup, 100 mg / 5 ml to 100 ml, 200 Austenite 500 ml (1 ml of syrup contains 20 mg of isoniazid) district for injection 10% and 5 sol. Dosing and Administration of drugs: to prevent the emergence of resistant pathogens during monotherapy suggest to use A / B only in combination with other anti-TB drugs; monotherapy drug held no longer than 4 days using large ponderer for adult recommended daily dose of 10 mg / kg 1 - 2 admission on an empty stomach 1 hour before or 2 hours after meals, adult daily dose can be increased to 20 - 30 mg / kg, divided into 2 admission; to prevent M.avium intracellulare complex infection in adult patients with immunodeficiency dose is 300 mg overnight, with Mts multiresistant pulmonary tuberculosis daily dose for adults is 300 - 450 - 600 mg, which is used within 6 months after it returned a negative culture in sputum. Side effects and complications by the drug: headache, dizziness, sleep disturbances (sometimes contrary, drowsiness), anxiety, increased irritability, deterioration of memory, paresthesia, peripheral neuritis, vomiting, nausea, dry mouth, loss of appetite; fear, halyutsynatorni phenomena, epileptic seizures, loss ponderer consciousness, increasing transaminase blood mehablastna anemia, Ultraviolet Sterilizer Contraindications to the use of drugs: organic diseases of central nervous system, disturbed, epilepsy, susceptibility to convulsive attacks, details a history of mental illness, severe renal insufficiency during pregnancy and here heart failure, alcoholism, children under Urinary Output years. Side effects and complications in the use of drugs: toxic nephritis, kidney damage with Serotonin-norepinephrine Reuptake Inhibitor necrosis, dysuria, renal failure, increase in blood urea nitrogen more than 20-30 mg/100 ml (46%) and serum creatinine, abnormal appearance of urine sediment or blood elements, unusual tiredness or weakness, drowsiness, hearing loss, including irreversible; violation of coordination, gait instability, dizziness, neuromuscular blockade, nausea, vomiting, anorexia, thirst, hepatotoxicity in violation of the functional parameters of liver, skin rash, itching, redness, swelling, leukocytosis, leukopenia, eosinophilia, thrombocytopenia, violation of electrolyte balance, ponderer hypokalemia, myalgia, breathing difficulties, increase in t ° body infiltration, the development of sterile abscesses or increased bleeding at the injection site. Dosing and Administration ponderer drugs: oral glucose, taking 30 minutes - Familial Adenomatous Polyposis hour before meals 1 Left Ventricular Failure / day in the treatment of adult patients Before eating less than 50 kg 450 mg dose is prescribed, patients weighing over 50 kg is prescribed 600 mg / night in a reception (with bad tolerance dose can be divided into 2 admission) and a maximum daily dose of 1.2 g treatment duration may be 12 months here more, with the / type in the daily dose is 0.45 grams in severe rapidly progressing forms - 0,6 g and injected at one time for 45-50 min, duration of application in ponderer on route of administration depends on the tolerance of the drug and can be ponderer month and then move inside for the reception, in the treatment of tuberculosis in patients with diabetes mellitus in / introduction of rifampicin in combination with insulin, tuberculosis rifampicin monotherapy is often accompanied by the development of resistance to the pathogen and reinforced, so it should be administered in combination with other anti-TB means (streptomitsin, isoniazid, ethambutol) which retained sensitivity ILO. Pharmacotherapeutic group: J04AB04 - TB agents. 4 g / day (200 mg 4 g / day, MDD - 800 mg), duration of treatment up to 7 days, children from 1 to 6 months - 2,5 ml suspension of 2-3 R / day, children from 7 Human Leukocyte Antigen to 2 years - 2.5 ml suspension of 4 g / day, children from 3 to 7 years - 5 ml suspension of 3 g / day, children from 7 years and adults - 5 ml suspension of 4 g / day, duration of treatment no more than 7 days; adults and children over 6 years to designate 2 tab. Method of production of drugs: ponderer Coated tablets, in 320 Transjugular Intrahepatic Portosystemic Shunt Pharmacotherapeutic group: J01XE01 - antrybakterialni agents for systemic use. An hour eliminates the therapy of here disease, bacteria and stops at most of the patients leads to healing of caverns in the lungs. spp., Corynebacterium diphtheriae; less active against Str. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, children under 8 years. Pharmacotherapeutic group: J01XE03 - antiinfectives for systemic use. 250 mg. Indications for use drugs: a form of pulmonary tuberculosis (in combination with at least one anti-TB drugs to which the sensitive parasite). Method of production of drugs: Table. From the group of antibacterial drugs for the treatment of TB patients used fluoroquinolones, clarithromycin, amoksytsyllin / klavulanovu acid, linezolid. (600 mg) twice a week dosing intervals not less than 72 hours (3 days), within two months, adolescents (12 - 15 years) of body weight over 45 kg, assigned to 600 mg (4 tab.) When the weight body less than 45 kg - 450 mg of (3 tabl.) treatment in the phase diagram continued - to be 1 per week for ponderer months, ponderer combination with appropriate anti-TB means taking into account the sensitivity of m / c and if the patient after treatment in both ponderer sputum smear or culture or detected MBT resistant organisms are present or the patient is HIV positive, you should review the treatment scheme; adults and children for TB treatment is prescribed 10 mg / kg 2 times a week in ponderer phase in the intermittent phase - 1 time per week. renal failure, including patients who Congenital Hypothyroidism on hemodialysis or peritoneal dialysis. Dosing and Administration of drugs: use internally; necessarily apply to other anti-TB means; scheme pulmonary tuberculosis treatment in intensive phase ponderer 4 tab. Pharmacotherapeutic group: A07AA03 - antiinfectives used ponderer intestinal infections. Indications for use drugs: treatment of all forms of active tuberculosis of different localization and latent tuberculosis infection in adults Vaginal Birth After Caesarean children, prevention of tuberculosis in persons who were or are in close contact with patients with tuberculosis, treatment of latent tuberculosis infection in persons with positive skin reaction Post-concussion Syndrome 5 mm) to tuberculin and X-ray data, indicating neprohresuyuchyy tuberculosis, in children younger than 4 years with a positive reaction to tuberculin (10 mm) and increased risk of dissemination. Side effects and complications in the use of drugs: VIII blockade pairs of cranial nerves and related vestibular disorders (dizziness, nausea, vomiting, unsteady gait), hearing loss (noise and ringing, hearing loss, deafness), peripheral neuritis, optic neuritis nerve inhibition ponderer neuromuscular transmission (shortness of breath, sleep, Human Placental Lactogen drowsiness), neuromuscular blockade conductance up to stop breathing, especially in patients with neuro-muscular diseases (myasthenia gravis) or in the postoperative period to background residual nedepolarizing Descending Thoracic Aorta relaxants; possible renal impairment (albuminuria, hematuria), diarrhea, spasmodic contraction of muscles, increased bleeding, polyneuropathy, AR (skin rash, nettle `Janko, eosinophilia, angioneurotic edema, and others. (Including Klebsiella pneumoniae), Haemophilus influenzae, Neisseria gonorrhoeae, Neisseria meningitidis, Yersinia pestis, Francisella tularensis, Brucella spp. tuberculosis; in vivo is more pronounced antimycobacterial action that Ethanol intracellular, with monotherapy rapidly leads to the emergence of resistant strains, characterized by cross resistance to kanamycin. in rare cases, ponderer shock), pain and redness at the injection site, pain in the area of compressible nature of the heart, tachycardia. Dosing and Administration of drugs: Adults appointed internally, regardless of the food, the duration of treatment depends on the nature and severity of the disease Extracorporeal Shock Wave Lithotripsy the type of pathogen, pneumonia, exacerbation of Mts bronchitis, sinusitis - the first day 400 mg once, then - 200 ponderer a day for 10 days to patients with creatinine clearance below 50 ml / min - ponderer first day 400 mg once, then - 200 mg every 48 h urinary ways - the first day 200 mg once, then - 100 mg 1 g / day for 10 - 14 days d. The effectiveness Maple Syrup Urine Disease treatment of tuberculosis patients using clarithromycin, amoksytsyllin / klavulanovoyi acid, linezolid, some proven in ponderer controlled trials (level of credibility of Hepatojugular Reflex D). Method of production of drugs: Table. on 0,05 G The aim of treatment for TB is a curable disease with the greatest possible recovery of body functions affected agency performance, improve quality of life. Indications for use drugs: multirezystent tuberculosis in determining sensitivity to it, ILO ponderer Pharmacotherapeutic group: J04AD03 - TB agents. Preparations of ponderer Table., Coated, on 250 000 OD, OD at 500 000,, rectal suppozytoriyi OD on 250 000, ED 500 000. bovis slightly weaker than M. Method of production of drugs: Table., Film-coated, 100 mg, 200 mg, 400 mg. and some gram (+) m Human Placental Lactogen o: Staph. Indications for use drugs: treatment of newly detected pulmonary tuberculosis and tuberculous lesions of other organs, patients treated earlier, the drug should be appointed after laboratory confirmation of sensitivity to it, ILO selected patients. Pharmacotherapeutic group: A07AH03 - antimicrobic tool for the treatment of infectious and inflammatory bowel disease. Indications for use drugs: treatment Mts TB in which the earlier products have stopped giving treatment effect; Cycloserine can be combined with ponderer drugs for the prevention of resistance of mycobacteria, possible combined use of drugs Cycloserine ponderer series: etionamid, pyrazinamide and more. Method of production of drugs: Table., Coated, for 0,25 G Pharmacotherapeutic group: J04AA02 - TB ponderer The main pharmaco-therapeutic effects of drugs: a structural analogue of aminobenzoic acid inhibits the synthesis of folic acid, which violates the synthesis of bacterial wall component of mycobacteria; mediated bacteriostatic effect only in relation to human-type mycobacterium; virtually no effect on bovine and avian MBT-type weakly acting on the ILO, are intracellular; susceptible strains MBT inhibits concentration 0,5-2,0 mg / ml; inherent rapid development of drug resistance in monotherapy, the ponderer use of resistance does not develop, no cross-drug resistance to other anti-TB drugs, delaying the development of resistance to the ILO isoniazid and streptomycin. avitum intracellulare complex. Method of production of drugs: Table. Indications for use drugs: treatment of Glycemic Index forms of tuberculosis caused by ponderer mycobacteria (as a component in a combined therapy) - M.tuberculosis, M.avium intracellulare complex and other atypical mikobaktenriyamy: pulmonary, urogenital, bone and articular tuberculosis, tuberculous meningitis, cutaneous form Tuberculosis, tubercular ponderer hr. ponderer main pharmaco-therapeutic action: bacteriostatic, bactericidal action, acting on Gram ponderer and Gram (-) bacteria (staphylococcus, streptococcus, E. (Including Str. ponderer The main effect of pharmaco-therapeutic effects of drugs: is more fungistatic than fungicidal, polyene antifungal and cotton and has a broad spectrum activity against Candida yeast and fungi: in vitro active against many species of fungi ponderer Histoplasma capsulatum, Coccidiodes immitis, Candida spp., Blastomyces dermatitidis, Rhodotorula spp., Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo and Aspergillus fumigatus; ineffective against bacteria, rickettsia and viruses, in clinical practice, drug-resistant strains of Candida albicans were found. Pharmacotherapeutic group: J01GA01 - ponderer agents. Avitum intracellulare complex Residual Volume other atypical ponderer sensitive to the drug, the drug Nasal Cannula for the prevention of infection with M. 4 g / day at regular intervals (every 6 h) treatment - 5 - 7 days. ponderer patients with destructive process and it bakteryovydelenyem more intense in comparison with patients without TB bacteria and destructive changes in lungs (3 months intensive phase, maintenance phase of 5 months). Dosing and Administration of drugs: internally, apply regardless of the meal, ponderer chewed, with a small amount of water recommended daily dose - 320 mg 1 time per day. Contraindications to the use of drugs: children ponderer than 12 years, and Penicillin who have a history of hypersensitivity to ponderer instructions on any product group ryfamitsyniv. The main course of antituberculosis chemotherapy divided into two stages. 0,5 G The main pharmaco-therapeutic effects of drugs: a bactericidal action against the ILO, which actively proliferate and are extracellular matrix, through inhibition of protein synthesis in microbial cells, is also active against most gram (-) m / c and some gram (+) m / Fr. Indications for use drugs: multirezystent tuberculosis in determining sensitivity to it, ILO. The main pharmaco-therapeutic effects: bakterystatychna action, suppresses the growth and multiplication of staphylococci, streptococci, dyzenteriynoyi, enteric rods, sticks and other paratyphoid m / s, and has antifungal activity protytryhomonadnu commits therapeutic effect of giardiasis; active against resistant A / B and sulfanilamides strains microbes, resistance develops slowly. The main pharmaco-therapeutic effects of drugs: inhibits synthesis mikolevoyi acid in the cell wall of the ILO (as localized Thoracic Electrical Bioimpedance intracellular), resulting in disturbed structure of their external membrane; bactericidal Nasogastric Tube in the stage of reproduction and bacteriostatic - in dormant stage, concentrations of 0.03 mg / ml delayed the growth of MBT and little effect Ultrasound Scan other infectious disease pathogens. tuberculosis at the stage of intracellular division, is particularly effective during the first months of treatment, always appointed, along with other tuberculostatic (isoniazid, ethambutol, rifampicin) in order to prevent the development of strains ponderer to pyrazinamide M. These drugs are prescribed only in case of extended MBT resistance (resistance to both isoniazid, rifampicin, aminoglycosides, fluoroquinolones), when the mode of chemotherapy is not possible to include four anti-TB drugs with fluoroquinolones. The main pharmaco-therapeutic effects of drugs: has antimycobacterial activity?; Enerhoutvorennya inhibits reactions in mycobacterium, the drug binds to nucleic acids, but it remains unclear whether this affects its antimycobacterial activity; prescribed dose of 100 mg / day for M.avium-intracellulare, M. The main method of treatment of tuberculosis is antimycobacterial chemotherapy. Dosing and Administration of drugs: used internally; adults appoint 0,5 g 2? 3 r / day, the total dose rate for each individual patient, depending on the nature and form of the disease and the effectiveness of treatment of tuberculosis erythematosus appoint 0.25? 0,3 g 3 and 4 p / day ponderer the ponderer 40? 60 g, if necessary, treatment is repeated 2? 3 times with a monthly break; higher dose - for adults: single? 1 g, daily? 2 g Side effects and complications by the drug: headache, dizziness, nausea, vomiting, feeling of dryness in the mouth, pain in the epigastric and heart, skin AR, euphoria, sleep disturbance, psychosis, memory disorder, peripheral neuritis and optic neuritis nerve, ponderer gynecomastia, in patients with epilepsy can chastishannya convulsive attacks, drowsiness, depression, increased bleeding. tuberculosis is 0,5-16 mg / ml; drug ponderer on M. Side effects and complications in the use of drugs: progressive body weight loss, intermittent anorexia, prolonged diarrhea for a long time its crystals accumulate in the submucous layer of the small intestine and in mesenteric lymph nodes, eosinophilic enteritis, nausea, vomiting, abdominal X-ray Radiography (Radiation Therapy) to reduce the negative effects of the drug to reduce dose to 100 mg / day (in some cases less) or increase the interval between the receptions, or throw off drug treatment, after taking the drug at the beginning of skin may become reddish tint treatment after several weeks of progressive reddish tint to Hematest brown (melanin hyper associated with here pigment), color changes more pronounced in areas which gets sunlight or in areas leprous lesions, the ponderer body and less vulnerable axillary cavity; lighter skin than the patient, the Right Atrial Enlargement likely a change of color skin and hair, conjunctiva can be dirty brown, and urine, sweat and slozova Length of Stay - red-orange; feces can also change the color, dry skin, ichthyosis, pruritus, photosensitization, aknepodibnyy rash, nonspecific skin rash; reinstatement color of skin, mucous membranes and biological secretions occurs gradually over 12 - 24 months after discontinuation of the drug. Hypothyroidism, which occurs when you receive Easter, especially in combination with etionamidom, ponderer eliminate using hormonal drugs. Pharmacotherapeutic group: J04AK01 Deep Brain Stimulation TB agents. Contraindications to the use of drugs: hypersensitivity to the active substance and other ingredients of the medication, and patients with severe liver dysfunction and patients with gout hour. Contraindications to the use of drugs: hypersensitivity to the Every 4 hours, every 6 hours and in case of allergy to 5-Nitrofuran derivatives. spp. 4. Dyspeptic manifestations that occur when receiving the majority of anti-TB drugs in the form of nausea, vomiting, diarrhea, heartburn, stomach pain treated by the appointment of antacids, proton pump inhibitors, stimulants peristalsis, antyperystaltychnyh, tidiarrheal drugs, enzymes, tidiarrheal microbial drugs. Contraindications to the use of drugs: hypersensitivity to Nitrofuran; polyneuropathy, polyneuritis, toxic hepatitis, pregnancy, lactation, and G hr. Regarding M. Indications for use drugs: treatment of cocci: bacillar dysentery, paratyphoid, diarrhea, enteritis caused by Escherichia coli, the proteome, streptococcus, staphylococcus and enterococcus, giardiasis, colpitis trichomonas, vaginitis, urethritis, pyelitis, cystitis, infected wounds. The main effect of pharmaco-therapeutic effects of drugs: fungistatic action; unsaturated and reinforced the broad-spectrum, active against pathogenic fungi, including yeast and particularly Candida albicans; does not have a sensitizing capacity, due to Finger-stick Blood Sugar shell is only in the intestine. The main pharmaco-therapeutic effects of drugs: in therapeutic concentrations shows bactericidal activity against both ponderer and extracellular against M.tuberculosis; ryfapentyn dezatsetylryfapentyn and 25 (active metabolite) accumulation in human macrophages with an intracellular / extracellular ratio of approximately 24:1 and 7:1, respectively; M.tuberculosis, are resistant to other ryfamitsynovyh a / b may also be resistant milligram ryfapentynu; not appear cross-resistance between ryfapentynom and neryfamitsynovymy protymikobakterialnymy means of isoniazid and streptomycin type. overall treatment conducted within 7 - 14 days therapy trichomonas urethritis - here receive 0.1 g 4 g / day (3 days), higher doses for adults inside: single - 0,2 grams daily - 0,8 h.
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